Detalhe da pesquisa
1.
Pharos 2023: an integrated resource for the understudied human proteome.
Nucleic Acids Res
; 51(D1): D1405-D1416, 2023 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36624666
2.
NCATS Inxight Drugs: a comprehensive and curated portal for translational research.
Nucleic Acids Res
; 50(D1): D1307-D1316, 2022 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34648031
3.
TCRD and Pharos 2021: mining the human proteome for disease biology.
Nucleic Acids Res
; 49(D1): D1334-D1346, 2021 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33156327
4.
The application of acute oral toxicity computational models in dangerous goods classification.
Toxicol Ind Health
; 39(12): 687-699, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37860984
5.
A Workflow of Integrated Resources to Catalyze Network Pharmacology Driven COVID-19 Research.
J Chem Inf Model
; 62(3): 718-729, 2022 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35057621
6.
Using in vitro ADME data for lead compound selection: An emphasis on PAMPA pH 5 permeability and oral bioavailability.
Bioorg Med Chem
; 56: 116588, 2022 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35030421
7.
Large-Scale Modeling of Multispecies Acute Toxicity End Points Using Consensus of Multitask Deep Learning Methods.
J Chem Inf Model
; 61(2): 653-663, 2021 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33533614
8.
Critical Assessment of Artificial Intelligence Methods for Prediction of hERG Channel Inhibition in the "Big Data" Era.
J Chem Inf Model
; 60(12): 6007-6019, 2020 12 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33259212
9.
SuperDRUG2: a one stop resource for approved/marketed drugs.
Nucleic Acids Res
; 46(D1): D1137-D1143, 2018 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29140469
10.
Exploring Activity Profiles of PAINS and Their Structural Context in Target-Ligand Complexes.
J Chem Inf Model
; 58(9): 1847-1857, 2018 09 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30105913
11.
The Catch-22 of Predicting hERG Blockade Using Publicly Accessible Bioactivity Data.
J Chem Inf Model
; 58(6): 1224-1233, 2018 06 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29772901
12.
WITHDRAWN--a resource for withdrawn and discontinued drugs.
Nucleic Acids Res
; 44(D1): D1080-6, 2016 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26553801
13.
Consideration of vendor-related differences in hepatic metabolic stability data to optimize early ADME screening in drug discovery.
SLAS Discov
; 29(1): 34-39, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37573009
14.
Development and validation of PAMPA-BBB QSAR model to predict brain penetration potential of novel drug candidates.
Front Pharmacol
; 14: 1291246, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38108064
15.
Validating ADME QSAR Models Using Marketed Drugs.
SLAS Discov
; 26(10): 1326-1336, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34176369
16.
Predicting liver cytosol stability of small molecules.
J Cheminform
; 12(1): 21, 2020 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33431020
17.
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
Sci Rep
; 10(1): 20713, 2020 11 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33244000
18.
How to Illuminate the Druggable Genome Using Pharos.
Curr Protoc Bioinformatics
; 69(1): e92, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31898878
19.
A Workflow of Integrated Resources to Catalyze Network Pharmacology Driven COVID-19 Research.
bioRxiv
; 2020 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33173863
20.
Pain-Prescription Differences - An Analysis of 500,000 Discharge Summaries.
Curr Drug Res Rev
; 11(1): 58-66, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30207223